MiR-155 Induction by F. novicida but Not the Virulent F. tularensis Results in SHIP Down-Regulation and Enhanced Pro-Inflammatory Cytokine Response

The intracellular Gram-negative bacterium Francisella tularensis causes the disease tularemia and is known for its ability to subvert host immune responses. Previous work from our laboratory identified the PI3K/Akt pathway and SHIP as critical modulators of host resistance to Francisella. Here, we s...

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Bibliographische Detailangaben
Hauptverfasser: Cremer, Thomas J., Ravneberg, David H., Clay, Corey D., Piper-Hunter, Melissa G., Marsh, Clay B., Elton, Terry S., Gunn, John S., Amer, Amal, Kanneganti, Thirumala-Devi, Schlesinger, Larry S., Butchar, Jonathan P., Tridandapani, Susheela
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794384/
https://ncbi.nlm.nih.gov/pubmed/20041145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008508
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