Cell Volume Decrease as a Link between Azaspiracid-Induced Cytotoxicity and c-Jun-N-Terminal Kinase Activation in Cultured Neurons

Azaspiracids (AZAs) are a group of marine toxins recently described that currently includes 20 members. Not much is known about their mechanism of action, although the predominant analog in nature, AZA-1 targets several organs in vivo, including the central nervous system, and exhibits high neurotox...

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Autori principali: Vale, Carmen, Nicolaou, Kyriacos C., Frederick, Michael O., Vieytes, Mercedes R., Botana, Luis M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Neurotoxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794333/
https://ncbi.nlm.nih.gov/pubmed/19815690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp246
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