Addition of Angiotensin Receptor Blockade or Mineralocorticoid Antagonism to Maximal Angiotensin-Converting Enzyme Inhibition in Diabetic Nephropathy

Aldosterone promotes glomerular and tubular sclerosis independent of angiotensin II in animal models of diabetic nephropathy. Most human studies testing the renoprotective benefit of adding an angiotensin receptor blocker or a mineralocorticoid receptor antagonist to a regimen based on inhibition of...

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Autori principali: Mehdi, Uzma F., Adams-Huet, Beverley, Raskin, Philip, Vega, Gloria L., Toto, Robert D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2009
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794224/
https://ncbi.nlm.nih.gov/pubmed/19926893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009070737
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