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Addition of Atrasentan to Renin-Angiotensin System Blockade Reduces Albuminuria in Diabetic Nephropathy

Although endothelin-receptor antagonists reduce albuminuria in diabetic nephropathy, fluid retention limits their use. Here, we examined the effect of atrasentan, a selective endothelin A receptor (ET(A)R) antagonist, on albuminuria in a randomized, double-blind, placebo-controlled trial of subjects...

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Autors principals: Kohan, Donald E., Pritchett, Yili, Molitch, Mark, Wen, Shihua, Garimella, Tushar, Audhya, Paul, Andress, Dennis L.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065231/
https://ncbi.nlm.nih.gov/pubmed/21372210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010080869
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