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Heterologous Expression Studies of Saccharomyces cerevisiae Reveal Two Distinct Trypanosomatid CaaX Protease Activities and Identify Their Potential Targets

The CaaX tetrapeptide motif typically directs three sequential posttranslational modifications, namely, isoprenylation, proteolysis, and carboxyl methylation. In all eukaryotic systems evaluated to date, two CaaX proteases (Rce1 and Ste24/Afc1) have been identified. Although the Trypanosoma brucei g...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mokry, David Z., Manandhar, Surya P., Chicola, Kristen A., Santangelo, George M., Schmidt, Walter K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794219/
https://ncbi.nlm.nih.gov/pubmed/19820121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00169-09
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