Modulation of the DNA-binding activity of Saccharomyces cerevisiae MSH2–MSH6 complex by the high-mobility group protein NHP6A, in vitro

DNA mismatch repair corrects mispaired bases and small insertions/deletions in DNA. In eukaryotes, the mismatch repair complex MSH2–MSH6 binds to mispairs with only slightly higher affinity than to fully paired DNA in vitro. Recently, the high-mobility group box1 protein, (HMGB1), has been shown to...

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Bibliographic Details
Main Authors: Labazi, Mohamed, Jaafar, Lahcen, Flores-Rozas, Hernan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794155/
https://ncbi.nlm.nih.gov/pubmed/19843605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp649
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