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High Rates and Substrate Selectivities in Water by Polyvinylimidazoles as Transaminase Enzyme Mimics with Hydrophobically Bound Pyridoxamine Derivatives as Coenzyme Mimics

[Image: see text] Free radical polymers of 4-vinylimidazole and copolymers with 1-dodecyl-4-vinylimidazole were used as enzyme mimics to transaminate pyruvic acid to alanine, phenylpyruvic acid to phenylalanine, and indole-3-pyruvic acid to tryptophan in water at pH 7.5 and 20 °C, using pyridoxamine...

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Detalhes bibliográficos
Main Authors: Skouta, Rachid, Wei, Sujun, Breslow, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794039/
https://ncbi.nlm.nih.gov/pubmed/19824661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9072589
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