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Enantioselective Transaminations by Dendrimeric Enzyme Mimics

PAMAM dendrimers have been constructed with a pyridoxamine core, and chiral capping amino groups. Transamination to form phenylalanine and alanine from their related ketoacids produced enantioselectivities induced by the formally remote chiral caps, supporting computer models that indicate folding o...

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Detalhes bibliográficos
Main Authors: Breslow, Ronald, Wei, Sujun, Kenesky, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031867/
https://ncbi.nlm.nih.gov/pubmed/18596840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2007.02.052
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