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Systemic properties of metabolic networks lead to an epistasis-based model for heterosis

The genetic and molecular approaches to heterosis usually do not rely on any model of the genotype–phenotype relationship. From the generalization of Kacser and Burns’ biochemical model for dominance and epistasis to networks with several variable enzymes, we hypothesized that metabolic heterosis co...

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Detalhes bibliográficos
Main Authors: Fiévet, Julie B., Dillmann, Christine, de Vienne, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793392/
https://ncbi.nlm.nih.gov/pubmed/19916003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00122-009-1203-2
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