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Systemic properties of metabolic networks lead to an epistasis-based model for heterosis

The genetic and molecular approaches to heterosis usually do not rely on any model of the genotype–phenotype relationship. From the generalization of Kacser and Burns’ biochemical model for dominance and epistasis to networks with several variable enzymes, we hypothesized that metabolic heterosis co...

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Autors principals: Fiévet, Julie B., Dillmann, Christine, de Vienne, Dominique
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793392/
https://ncbi.nlm.nih.gov/pubmed/19916003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00122-009-1203-2
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