Anchorage of Vinculin to Lipid Membranes Influences Cell Mechanical Properties

The focal adhesion protein vinculin (1066 residues) can be separated into a 95-kDa head and a 30-kDa tail domain. Vinculin's lipid binding sites localized on the tail, helix 3 (residues 944–978) and the unstructured C-terminal arm (residues 1052–1066, the so-called lipid anchor), influence foca...

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Bibliografske podrobnosti
Main Authors: Diez, Gerold, Kollmannsberger, Philip, Mierke, Claudia T., Koch, Thorsten M., Vali, Hojatollah, Fabry, Ben, Goldmann, Wolfgang H.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2009
Teme:
Cellular Biophysics and Electrophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793365/
https://ncbi.nlm.nih.gov/pubmed/20006947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.039
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