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Phosphatidylserine Regulation of Ca(2+)-triggered Exocytosis and Fusion Pores in PC12 Cells

The synaptic vesicle protein synaptotagmin I (Syt I) binds phosphatidylserine (PS) in a Ca(2+)-dependent manner. This interaction is thought to play a role in exocytosis, but its precise functions remain unclear. To determine potential roles for Syt I-PS binding, we varied the PS content in PC12 cel...

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Hlavní autoři: Zhang, Zhen, Hui, Enfu, Chapman, Edwin R., Jackson, Meyer B.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793286/
https://ncbi.nlm.nih.gov/pubmed/19828732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-08-0691
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