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Mannose 6-phosphate receptor targeting and its applications in human diseases

The cation-independent mannose 6-phosphate receptor is a multifunctional protein which binds at the cell surface to two distinct classes of ligands, the mannose 6-phosphate (M6P) bearing proteins and IGF-II. Its major function is to bind and transport M6P-enzymes to lysosomes, but it can also modula...

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Détails bibliographiques
Auteurs principaux: Gary-Bobo, Magali, Nirdé, Philippe, Jeanjean, Audrey, Morère, Alaih, Garcia, Marcel
Format: Artigo
Langue:Inglês
Publié: Bentham Science Publishers 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793280/
https://ncbi.nlm.nih.gov/pubmed/18220730
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