Characterization of TEM1/endosialin in human and murine brain tumors

BACKGROUND: TEM1/endosialin is an emerging microvascular marker of tumor angiogenesis. We characterized the expression pattern of TEM1/endosialin in astrocytic and metastatic brain tumors and investigated its role as a therapeutic target in human endothelial cells and mouse xenograft models. METHODS...

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Hoofdauteurs: Carson-Walter, Eleanor B, Winans, Bethany N, Whiteman, Melissa C, Liu, Yang, Jarvela, Sally, Haapasalo, Hannu, Tyler, Betty M, Huso, David L, Johnson, Mahlon D, Walter, Kevin A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793264/
https://ncbi.nlm.nih.gov/pubmed/19948061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-417
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