Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins

Neuregulin-1 (NRG1) is a potential therapeutic agent for the treatment of doxorubicin (Dox)-induced heart failure. NRG1, however, activates the erbB2 receptor, which is frequently overexpressed in breast cancers. It is, therefore, important to understand how NRG1, via erbB2, protects the heart again...

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Main Authors: Bian, Yun, Sun, Maoyun, Silver, Marcy, Ho, Kalon K. L., Marchionni, Mark A., Caggiano, Anthony O., Stone, James R., Amende, Ivo, Hampton, Thomas G., Morgan, James P., Yan, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
Assuntos:
Translational Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793128/
https://ncbi.nlm.nih.gov/pubmed/19801490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01010.2008
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