A large-conductance (BK) potassium channel subtype affects both growth and mineralization of human osteoblasts

The pharmacology of the large-conductance K(+) (BK) channel in human osteoblasts is not well defined, and its role in bone is speculative. Here we assess BK channel properties in MG63 cells and primary human osteoblasts and determine whether pharmacological modulation affects cell function. We used...

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Detalhes bibliográficos
Main Authors: Henney, Neil C., Li, Bo, Elford, Carole, Reviriego, Pablo, Campbell, Anthony K., Wann, Kenneth T., Evans, Bronwen A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Membrane Transporters, Ion Channels, and Pumps
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793057/
https://ncbi.nlm.nih.gov/pubmed/19776394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00311.2009
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