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A regulatory role of LPCAT1 in the synthesis of inflammatory lipids, PAF and LPC, in the retina of diabetic mice

Platelet-activating factor (PAF) and lysophosphatidylcholine (LPC) are potent inflammatory lipids. Elevated levels of PAF and LPC are associated with the onset of diabetic retinopathy and neurodegeneration. However, the molecular mechanisms underlying such defects remain elusive. LPCAT1 is a newly r...

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Bibliografiske detaljer
Main Authors: Cheng, Long, Han, Xiao, Shi, Yuguang
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793047/
https://ncbi.nlm.nih.gov/pubmed/19773578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00475.2009
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