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LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice
Respiratory distress syndrome (RDS), which is the leading cause of death in premature infants, is caused by surfactant deficiency. The most critical and abundant phospholipid in pulmonary surfactant is saturated phosphatidylcholine (SatPC), which is synthesized in alveolar type II cells de novo or b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860922/ https://ncbi.nlm.nih.gov/pubmed/20407208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38061 |
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