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Bone Marrow Osteoblastic Niche: A New Model to Study Physiological Regulation of Megakaryopoiesis

BACKGROUND: The mechanism by which megakaryocytes (Mks) proliferate, differentiate, and release platelets into circulation are not well understood. Growing evidence indicates that a complex regulatory mechanism, involving cellular interactions, composition of the extracellular matrix and physical pa...

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Detalhes bibliográficos
Main Authors: Pallotta, Isabella, Lovett, Michael, Rice, William, Kaplan, David L., Balduini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793008/
https://ncbi.nlm.nih.gov/pubmed/20027303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008359
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