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Palladium-Catalyzed Enantioselective Addition of Two Distinct Nucleophiles across Alkenes Capable of Quinone Methide Formation

A sequential intramolecular-intermolecular enantioselective alkene difunctionalization reaction has been developed which is thought to proceed through Pd-catalyzed quinone methide formation. The synthesis of new chiral heterocyclic compounds with adjacent chiral centers is achieved in enantiomeric r...

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Main Authors: Jensen, Katrina H., Pathak, Tejas P., Zhang, Yang, Sigman, Matthew S.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792916/
https://ncbi.nlm.nih.gov/pubmed/19902942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909030c
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