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Limited Roles of Rdh8, Rdh12, and Abca4 in all-trans-Retinal Clearance in Mouse Retina

PURPOSE: Although the retinoid cycle is essential for vision, all-trans-retinal and the side products of this cycle are toxic. Delayed clearance of all-trans-retinal causes accumulation of its condensation products, A2E, and all-trans-retinal dimer (RALdi), both associated with human macular degener...

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Detaylı Bibliyografya
Asıl Yazarlar: Maeda, Akiko, Golczak, Marcin, Maeda, Tadao, Palczewski, Krzysztof
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792889/
https://ncbi.nlm.nih.gov/pubmed/19553623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-3944
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