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A mathematical feasibility argument for the use of aptamers in chemotherapy and imaging
A challenge for drug design is to create molecules with optimal functions that also partition efficiently into the appropriate in vivo compartment(s). This is particularly true in cancer treatments because cancer cells upregulate their expression of multidrug resistance transporters, which necessita...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792639/ https://ncbi.nlm.nih.gov/pubmed/19540245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2009.05.006 |
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