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Synthesis and In Vitro Autoradiographic Evaluation of a Novel High-affinity Radioiodinated Ligand for Imaging Brain Cannabinoid Subtype-1 Receptors

There is strong interest to study the involvement of brain cannabinoid subtype-1 (CB(1)) receptors in neuropsychiatric disorders with single photon emission computed tomography (SPECT) and a suitable radioligand. Here we report the synthesis of a novel high-affinity radioiodinated CB(1) receptor lig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Donohue, Sean R., Varnäs, Katarina, Jia, Zhisheng, Gulyas, Balazs, Pike, Victor W., Halldin, Christer
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792201/
https://ncbi.nlm.nih.gov/pubmed/19767206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.08.092
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