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Structural determinants of ion permeation in CRAC channels

CRAC channels generate Ca(2+) signals critical for the activation of immune cells and exhibit an intriguing pore profile distinguished by extremely high Ca(2+) selectivity, low Cs(+) permeability, and small unitary conductance. To identify the ion conduction pathway and gain insight into the structu...

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Detalhes bibliográficos
Main Authors: McNally, Beth A., Yamashita, Megumi, Engh, Anita, Prakriya, Murali
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792162/
https://ncbi.nlm.nih.gov/pubmed/20018736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909574106
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