Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages

Cathelicidins are CHDP with essential roles in innate host defense but also more recently associated with the pathogenesis of certain chronic diseases. These peptides have microbicidal potential and the capacity to modulate innate immunity and inflammatory processes. PMN are key innate immune effect...

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Bibliographic Details
Main Authors: Li, Hsin-Ni, Barlow, Peter G., Bylund, Johan, Mackellar, Annie, Björstad, Åse, Conlon, James, Hiemstra, Pieter S., Haslett, Chris, Gray, Mohini, Simpson, A. John, Rossi, Adriano G., Davidson, Donald J.
Format: Artigo
Language:Inglês
Published: The Society for Leukocyte Biology 2009
Subjects:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791992/
https://ncbi.nlm.nih.gov/pubmed/19581375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0209050
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