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The role of the Src family kinase Lyn in the immunomodulatory activities of cathelicidin peptide LL-37 on monocytic cells

Cathelicidin LL-37 is a multifunctional, immunomodulatory and antimicrobial host-defense peptide of the human immune system. Here, we identified the role of SFKs in mediating the chemokine induction activity of LL-37 in monocytic cells. LL-37 induced SFK phosphorylation; and chemical inhibitors of S...

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Bibliografski detalji
Glavni autori: Nijnik, Anastasia, Pistolic, Jelena, Cho, Patricia, Filewod, Niall C. J., Falsafi, Reza, Ramin, Alexander, Harder, Kenneth W., Hancock, Robert E. W.
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409631/
https://ncbi.nlm.nih.gov/pubmed/22246800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0411191
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