PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways

Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits platelet response to collagen and may also inhibit two other major platelet agonists ADP and thrombin although this has been less well explored. We hypothesized that the combined effect of inhibiting these three platelet activating pat...

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Hlavní autoři: Jones, Chris I., Garner, Stephen F., Moraes, Leonardo A., Kaiser, William J., Rankin, Angela, Ouwehand, Willem H., Goodall, Alison H., Gibbins, Jonathan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Science B.V 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791847/
https://ncbi.nlm.nih.gov/pubmed/19850043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.10.037
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