MET/PKCß expression correlate with metastasis and inhibition is synergistic in lung cancer

BACKGROUND: Treatment of non-small cell lung cancer (NSCLC) remains a difficult task in oncology. Targeted inhibition of oncogenic proteins is promising. In this study, we evaluate the expression of MET and PKCß and in vitro effects of their inhibition using SU11274 and enzastaurin (LY317615.HCl) re...

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Detalhes bibliográficos
Main Authors: Faoro, Leonardo, Cervantes, Gustavo M., Ferguson, Benjamin D., Seiwert, Tanguy Y., Yala, Soheil, Vigneswaran, Wicki T., Westerhoff, Maria, Tretiakova, Maria S., Ferguson, Mark K., Moura, Glaci L., Husain, Aliya N., Vokes, Everett E., Salgia, Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791827/
https://ncbi.nlm.nih.gov/pubmed/19955662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.57857
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