The Gabapentin Receptor α2δ-1 is the Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis

Synapses are asymmetric cellular adhesions that are critical for nervous system development and function, but the mechanisms that induce their formation are not well understood. We have previously identified thrombospondin as an astrocyte-secreted protein that promotes CNS synaptogenesis. Here we id...

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Autors principals: Eroglu, Çagla, Allen, Nicola J., Susman, Michael W., O’Rourke, Nancy A., Park, Chan Young, Özkan, Engin, Chakraborty, Chandrani, Mulinyawe, Sara B., Annis, Douglas S., Huberman, Andrew D., Green, Eric M., Lawler, Jack, Dolmetsch, Ricardo, Garcia, K. Christopher, Smith, Stephen J., Luo, Z. David, Rosenthal, Arnon, Mosher, Deane F., Barres, Ben A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791798/
https://ncbi.nlm.nih.gov/pubmed/19818485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.09.025
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