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Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice

During injury to the nervous system, innate immune cells mediate phagocytosis of debris, cytokine production, and axon regeneration. In the neuro-degenerative disease amyotrophic lateral sclerosis (ALS), innate immune cells in the CNS are activated. However, the role of innate immunity in the periph...

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Главные авторы: Chiu, Isaac M., Phatnani, Hemali, Kuligowski, Michael, Tapia, Juan C., Carrasco, Monica A., Zhang, Ming, Maniatis, Tom, Carroll, Michael C.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791631/
https://ncbi.nlm.nih.gov/pubmed/19933335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911405106
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