Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration

Tetherin is an IFN-inducible restriction factor that inhibits HIV-1 particle release in the absence of the HIV-1 countermeasure, viral protein U (Vpu). Although ubiquitous in HIV-1 and simian immunodeficiency viruses from chimpanzees, greater spot nosed monkeys, mustached monkeys, and Mona monkeys,...

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Main Authors: Gupta, Ravindra K., Mlcochova, Petra, Pelchen-Matthews, Annegret, Petit, Sarah J., Mattiuzzo, Giada, Pillay, Deenan, Takeuchi, Yasuhiro, Marsh, Mark, Towers, Greg J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2009
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791628/
https://ncbi.nlm.nih.gov/pubmed/19864625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907075106
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