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A kinetic and thermodynamic understanding of O(2) tolerance in [NiFe]-hydrogenases

In biology, rapid oxidation and evolution of H(2) is catalyzed by metalloenzymes known as hydrogenases. These enzymes have unusual active sites, consisting of iron complexed by carbonyl, cyanide, and thiolate ligands, often together with nickel, and are typically inhibited or irreversibly damaged by...

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Detalhes bibliográficos
Main Authors: Cracknell, James A., Wait, Annemarie F., Lenz, Oliver, Friedrich, Bärbel, Armstrong, Fraser A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791605/
https://ncbi.nlm.nih.gov/pubmed/19934053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905959106
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