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Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins

We used single-molecule FRET in combination with other biophysical methods and molecular simulations to investigate the effect of temperature on the dimensions of unfolded proteins. With single-molecule FRET, this question can be addressed even under near-native conditions, where most molecules are...

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Bibliographische Detailangaben
Hauptverfasser: Nettels, Daniel, Müller-Späth, Sonja, Küster, Frank, Hofmann, Hagen, Haenni, Dominik, Rüegger, Stefan, Reymond, Luc, Hoffmann, Armin, Kubelka, Jan, Heinz, Benjamin, Gast, Klaus, Best, Robert B., Schuler, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791578/
https://ncbi.nlm.nih.gov/pubmed/19933333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900622106
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