Gamma-IFN-inducible-lysosomal thiol reductase modulates acidic proteases and HLA class II antigen processing in melanoma

HLA class II-restricted antigen (Ag) processing and presentation are important for the activation of CD4+ T cells, which are the central orchestrating cells of immune responses. The majority of melanoma cells either expresses, or can be induced to express, HLA class II proteins. Thus, they are prime...

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Hlavní autoři: Goldstein, Oliver G., Hajiaghamohseni, Laela M., Amria, Shereen, Sundaram, Kumaran, Reddy, Sakamuri V., Haque, Azizul
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791504/
https://ncbi.nlm.nih.gov/pubmed/18343923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0483-8
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