Common Genetic Variation and the Control of HIV-1 in Humans

To extend the understanding of host genetic determinants of HIV-1 control, we performed a genome-wide association study in a cohort of 2,554 infected Caucasian subjects. The study was powered to detect common genetic variants explaining down to 1.3% of the variability in viral load at set point. We...

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Detalhes bibliográficos
Main Authors: Fellay, Jacques, Ge, Dongliang, Shianna, Kevin V., Colombo, Sara, Ledergerber, Bruno, Cirulli, Elizabeth T., Urban, Thomas J., Zhang, Kunlin, Gumbs, Curtis E., Smith, Jason P., Castagna, Antonella, Cozzi-Lepri, Alessandro, De Luca, Andrea, Easterbrook, Philippa, Günthard, Huldrych F., Mallal, Simon, Mussini, Cristina, Dalmau, Judith, Martinez-Picado, Javier, Miro, José M., Obel, Niels, Wolinsky, Steven M., Martinson, Jeremy J., Detels, Roger, Margolick, Joseph B., Jacobson, Lisa P., Descombes, Patrick, Antonarakis, Stylianos E., Beckmann, Jacques S., O'Brien, Stephen J., Letvin, Norman L., McMichael, Andrew J., Haynes, Barton F., Carrington, Mary, Feng, Sheng, Telenti, Amalio, Goldstein, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2791220/
https://ncbi.nlm.nih.gov/pubmed/20041166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000791
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