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Cyclin E Is Stabilized in Response to Replication Fork Barriers Leading to Prolonged S Phase Arrest
Cyclin E is a regulator of cyclin-dependent protein kinases (Cdks) and is involved in mediating the cell cycle transition from G(1) to S phase. Here, we describe a novel function for cyclin E in the long term maintenance of checkpoint arrest in response to replication barriers. Exposure of cells to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790962/ https://ncbi.nlm.nih.gov/pubmed/19812034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035949 |
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