Differential Effects of Lysophosphatidic Acid and Phosphatidylinositol 4,5-Bisphosphate on Actin Dynamics by Direct Association with the Actin-binding Protein Villin

We have previously reported that the epithelial cell-specific actin-binding protein villin directly associates with phosphatidylinositol 4,5-bisphosphate (PIP(2)) through three binding sites that overlap with actin-binding sites in villin. As a result, association of villin with PIP(2) in hibits act...

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Autors principals: Tomar, Alok, George, Sudeep P., Mathew, Sijo, Khurana, Seema
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Accelerated Publications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790956/
https://ncbi.nlm.nih.gov/pubmed/19808673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.060830
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