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An Alu-derived intronic splicing enhancer facilitates intronic processing and modulates aberrant splicing in ATM
We have previously reported a natural GTAA deletion within an intronic splicing processing element (ISPE) of the ataxia telangiectasia mutated (ATM) gene that disrupts a non-canonical U1 snRNP interaction and activates the excision of the upstream portion of the intron. The resulting pre-mRNA splici...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790898/ https://ncbi.nlm.nih.gov/pubmed/19773425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp778 |
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