Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions

The wobble uridine of certain bacterial and mitochondrial tRNAs is modified, at position 5, through an unknown reaction pathway that utilizes the evolutionarily conserved MnmE and GidA proteins. The resulting modification (a methyluridine derivative) plays a critical role in decoding NNG/A codons an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Moukadiri, Ismaïl, Prado, Silvia, Piera, Julio, Velázquez-Campoy, Adrián, Björk, Glenn R., Armengod, M.-Eugenia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Nucleic Acid Enzymes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790889/
https://ncbi.nlm.nih.gov/pubmed/19767610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp762
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