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The nature of cell-cycle checkpoints: facts and fallacies
The concept of checkpoint controls revolutionized our understanding of the cell cycle. Here we revisit the defining features of checkpoints and argue that failure to properly appreciate the concept is leading to misinterpretation of experimental results. We illustrate, using the mitotic checkpoint,...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790835/ https://ncbi.nlm.nih.gov/pubmed/19930621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol195 |
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