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The nature of cell-cycle checkpoints: facts and fallacies

The concept of checkpoint controls revolutionized our understanding of the cell cycle. Here we revisit the defining features of checkpoints and argue that failure to properly appreciate the concept is leading to misinterpretation of experimental results. We illustrate, using the mitotic checkpoint,...

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Autori principali: Khodjakov, Alexey, Rieder, Conly L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790835/
https://ncbi.nlm.nih.gov/pubmed/19930621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol195
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