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Phosphorylation of Ser205 by the protein kinase CK2 persists on Pax3-FOXO1, but not Pax3, throughout early myogenic differentiation

The myogenic transcription factor Pax3 plays an essential role in early skeletal muscle development and is a key component in Alveolar rhabdomyosarcoma (ARMS), a childhood solid muscle tumor. ARMS is characterized by a t(2;13) chromosomal translocation resulting in the fusion of the 5′ Pax3 sequence...

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Autors principals: DIETZ, Kevin N., MILLER, Patrick J., HOLLENBACH, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790557/
https://ncbi.nlm.nih.gov/pubmed/19904978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9012947
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