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Evolution of an enzyme active site: The structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase

Muconate lactonizing enzyme (MLE), a component of the β-ketoadipate pathway of Pseudomonas putida, is a member of a family of related enzymes (the “enolase superfamily”) that catalyze the abstraction of the α-proton of a carboxylic acid in the context of different overall reactions. New untwinned cr...

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Bibliografische gegevens
Hoofdauteurs: Hasson, Miriam Sarah, Schlichting, Ilme, Moulai, Javad, Taylor, Kirk, Barrett, William, Kenyon, George L., Babbitt, Patricia C., Gerlt, John A., Petsko, Gregory A., Ringe, Dagmar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC27905/
https://ncbi.nlm.nih.gov/pubmed/9724714
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