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Derivation of an amino acid similarity matrix for peptide:MHC binding and its application as a Bayesian prior
BACKGROUND: Experts in peptide:MHC binding studies are often able to estimate the impact of a single residue substitution based on a heuristic understanding of amino acid similarity in an experimental context. Our aim is to quantify this measure of similarity to improve peptide:MHC binding predictio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790471/ https://ncbi.nlm.nih.gov/pubmed/19948066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-394 |
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