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Using a water-immiscible ionic liquid to improve asymmetric reduction of 4-(trimethylsilyl)-3-butyn-2-one catalyzed by immobilized Candida parapsilosis CCTCC M203011 cells

BACKGROUND: Whole cells are usually employed for biocatalytic reduction reactions to ensure efficient coenzyme regeneration and to avoid problems with enzyme purification and stability. The efficiency of whole cell-catalyzed bioreduction is frequently restricted by pronounced toxicity of substrate a...

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Detalhes bibliográficos
Main Authors: Lou, Wen-Yong, Chen, Lei, Zhang, Bo-Bo, Smith, Thomas J, Zong, Min-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790445/
https://ncbi.nlm.nih.gov/pubmed/19849833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-90
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