Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphé neurones and cranial motoneurones

In this study, we elucidate the roles of the winged-helix transcription factor Foxa2 in ventral CNS development in zebrafish. Through cloning of monorail (mol), which we find encodes the transcription factor Foxa2, and phenotypic analysis of mol(-/-) embryos, we show that floorplate is induced in th...

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Detalhes bibliográficos
Main Authors: Norton, Will H., Mangoli, Maryam, Lele, Zsolt, Pogoda, Hans-Martin, Diamond, Brianne, Mercurio, Sara, Russell, Claire, Teraoka, Hiroki, Stickney, Heather L., Rauch, Gerd-Jörg, Heisenberg, Carl-Philipp, Houart, Corinne, Schilling, Thomas F., Frohnhoefer, Hans-Georg, Rastegar, Sepand, Neumann, Carl J., Gardiner, R. Mark, Strähle, Uwe, Geisler, Robert, Rees, Michelle, Talbot, William S., Wilson, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790417/
https://ncbi.nlm.nih.gov/pubmed/15677724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.01611
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