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Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites

Leucine-rich repeat containing proteins are central to host defense in plants and animals. We show that in the mosquito Anopheles gambiae, two such proteins that antagonize malaria parasite infections, LRIM1 and APL1C, circulate in the hemolymph as a high molecular weight complex held together by di...

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Autors principals: Povelones, Michael, Waterhouse, Robert M., Kafatos, Fotis C., Christophides, George K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790318/
https://ncbi.nlm.nih.gov/pubmed/19264986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1171400
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