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Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer’s disease

Heme-a, is the heme prosthetic group of cytochrome c oxidase (COX), the terminal complex of the mitochondrial electron transport chain. We measured heme-a levels in postmortem brain tissue from nine patients diagnosed with dementia: Alzheimer’s disease (AD) was the primary diagnosis in five, AD/Diff...

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Main Authors: Dwyer, Barney E., Stone, Meghan L., Gorman, Nadia, Sinclair, Peter R., Perry, George, Smith, Mark A., Zhu, Xiongwei
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790081/
https://ncbi.nlm.nih.gov/pubmed/19539709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.06.007
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