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NMR structural characterization of substrates bound to the alpha-2, 6-sialyltransferase, ST6Gal-I

The alpha-2,6-sialyltransferase, ST6Gal-I, is a key enzyme that regulates the distribution of sialic acid-containing molecules on mammalian cell surfaces. However, the fact that its native form is membrane-bound and glycosylated has made structural characterization by X-ray crystallography of this e...

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Detalhes bibliográficos
Main Authors: Liu, Shan, Meng, Lu, Moremen, Kelley W., Prestegard, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790006/
https://ncbi.nlm.nih.gov/pubmed/19845399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015154
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