Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli

BACKGROUND: The presence of terminal, surface-exposed sialic acid moieties can greatly enhance the in vivo half-life of glycosylated biopharmaceuticals and improve their therapeutic efficacy. Complete and homogeneous sialylation of glycoproteins can be efficiently performed enzymically in vitro but...

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Detaylı Bibliyografya
Asıl Yazarlar: Skretas, Georgios, Carroll, Sean, DeFrees, Shawn, Schwartz, Marc F, Johnson, Karl F, Georgiou, George
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762462/
https://ncbi.nlm.nih.gov/pubmed/19788761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-8-50
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